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Home > NC Providers > Cardiologists

Dr. Karen P. Alexander, MD

Accepting New Patients

(436 Ratings)

Specializes in: Cardiology (Heart Disease)

Duke University School of Medicine (1992)

2400 Pratt Street Room 0311 Terrace Level
Durham, NC 27705

(919) 668-8871

Dr. Karen P. Alexander, MD is a cardiologist in Durham, NC specializing in cardiology (heart disease). She graduated from Duke University School of Medicine in 1992 and has 34 years of experience. Dr. Karen P. Alexander, MD is affiliated with Duke Health.

Office Locations

2400 Pratt Street Room 0311 Terrace Level
Durham, NC 27705

(919) 668-8871

(919) 668-7056

open_in_new

Duke Health

5601 Arringdon Park Drive
Morrisville, NC 27560

(919) 997-3100

(919) 997-3149

open_in_new

In The News (see more mentions in the news)

“"Cardiology has been blessed with a lot of progress and research and drug development," said Dr. Karen Alexander, who teaches geriatric cardiology at Duke University.”—"New Insights Into Older Hearts", New York Times, February 2025

“"Very few people start a statin after age 75 because we don't have any proof that this drug improves the health of older adults," said Dr. Karen Alexander, a Duke cardiologist in Durham and lead...”—"Clinical research programs aim to improve lives, recruit local participants at NCRC - Salisbury Post", Salisbury Post, June 2022

“This is important to do before adding one more medication to the list of medicines older adults are often already taking," Dr. Karen Alexander, a geriatric cardiologist at Duke University Medical...”—"Essentia Health enrolling older adults for clinical study", Brainerd Dispatch, October 2020

Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	402

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	440

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	98
Female	164

**Ethnicity**
Non-Hispanic White	209
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	118
From 75 to 84	88
85 and over	30
Less than 65	26

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2013

Hypertension	75
High Cholesterol	70
Stroke	5
Ischemic Heart Disease	63
Depression	19
Chronic Kidney Disease	23
Asthma	6
Osteoperosis	6
Atrial Fibrilation	20
Heart Failure	28
Chronic Obstructive Pulmonary Disease	11
Diabetes	36
Dementia	9
Cancer	12

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	413

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	89
Female	163

**Ethnicity**
Non-Hispanic White	199
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	116
From 75 to 84	73
85 and over	36
Less than 65	27

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2014

Hypertension	75
High Cholesterol	75
Stroke	6
Ischemic Heart Disease	63
Depression	23
Chronic Kidney Disease	23
Asthma	6
Osteoperosis	11
Atrial Fibrilation	23
Heart Failure	25
Chronic Obstructive Pulmonary Disease	11
Diabetes	34
Dementia	8
Cancer	12

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	388

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	196
Female	276

**Ethnicity**
Non-Hispanic White	376
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	220
From 75 to 84	146
85 and over	72
Less than 65	34

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2015

Hypertension	75
High Cholesterol	70
Stroke	8
Ischemic Heart Disease	64
Depression	19
Chronic Kidney Disease	26
Asthma	12
Osteoperosis	7
Atrial Fibrilation	25
Heart Failure	28
Chronic Obstructive Pulmonary Disease	14
Diabetes	32
Dementia	7
Cancer	10

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	423

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	104
Female	146

**Ethnicity**
Non-Hispanic White	196
Black	42
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	123
From 75 to 84	74
85 and over	37
Less than 65	16

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2016

Hypertension	75
High Cholesterol	72
Stroke	7
Ischemic Heart Disease	62
Depression	20
Chronic Kidney Disease	31
Asthma	14
Osteoperosis	9
Atrial Fibrilation	24
Heart Failure	31
Chronic Obstructive Pulmonary Disease	11
Diabetes	35
Dementia	7
Cancer	11

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	447

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	112
Female	146

**Ethnicity**
Non-Hispanic White	202
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	135
From 75 to 84	74
85 and over	32
Less than 65	17

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2017

Hypertension	75
High Cholesterol	52
Stroke	6
Ischemic Heart Disease	59
Depression	21
Chronic Kidney Disease	32
Asthma	9
Osteoperosis	10
Atrial Fibrilation	23
Heart Failure	29
Chronic Obstructive Pulmonary Disease	11
Diabetes	31
Dementia	9
Cancer	10

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	431

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	112
Female	154

**Ethnicity**
Non-Hispanic White	216
Black	37
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	136
From 75 to 84	78
85 and over	40
Less than 65	12

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2018

Hypertension	74
High Cholesterol	65
Stroke	0
Ischemic Heart Disease	61
Depression	24
Chronic Kidney Disease	35
Asthma	8
Osteoperosis	9
Atrial Fibrilation	26
Heart Failure	30
Chronic Obstructive Pulmonary Disease	11
Diabetes	32
Dementia	10
Cancer	11

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	434

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	107
Female	167

**Ethnicity**
Non-Hispanic White	225
Black	34
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	123
From 75 to 84	99
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2019

Hypertension	75
High Cholesterol	64
Stroke	5
Ischemic Heart Disease	59
Depression	21
Chronic Kidney Disease	35
Asthma	6
Osteoperosis	13
Atrial Fibrilation	24
Heart Failure	27
Chronic Obstructive Pulmonary Disease	11
Diabetes	32
Dementia	11
Cancer	14

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	320

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	93
Female	149

**Ethnicity**
Non-Hispanic White	205
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	106
From 75 to 84	90
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2020

Hypertension	75
High Cholesterol	57
Stroke	0
Ischemic Heart Disease	51
Depression	19
Chronic Kidney Disease	32
Asthma	6
Osteoperosis	11
Atrial Fibrilation	23
Heart Failure	24
Chronic Obstructive Pulmonary Disease	6
Diabetes	32
Dementia	7
Cancer	12

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	347

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	98
Female	152

**Ethnicity**
Non-Hispanic White	217
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	101
From 75 to 84	108
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2021

Hypertension	74
High Cholesterol	63
Stroke	5
Ischemic Heart Disease	56
Depression	16
Chronic Kidney Disease	32
Asthma	5
Osteoperosis	10
Atrial Fibrilation	22
Heart Failure	24
Chronic Obstructive Pulmonary Disease	8
Diabetes	24
Dementia	8
Cancer	13

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	338

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Male	95
Female	174

**Ethnicity**
Non-Hispanic White	234
Black	21
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	111
From 75 to 84	118
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD in 2022

Hypertension	75
High Cholesterol	75
Stroke	6
Ischemic Heart Disease	46
Depression	16
Chronic Kidney Disease	22
Asthma	7
Osteoperosis	20
Atrial Fibrilation	35
Heart Failure	20
Chronic Obstructive Pulmonary Disease	13
Diabetes	21
Dementia	0
Cancer	15

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. Karen P. Alexander, MD for Medicare patients.

doctor visit	398

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. Karen P. Alexander, MD.

**Gender**
Female	153
Male	100

**Ethnicity**
Black / African American	12
Asian / Pacific Islander	0
Non-Hispanic White	207
Native American / Alaskan Native	0
Hispanic	0
Other	0

**Age**
85 and over	22
75 to 84	86
Less than 65	12
65 to 74	117

Average of Total of Conditions of Medicare patients treated by Dr. Karen P. Alexander, MD From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Karen P. Alexander, MD treated were hypertension, high cholesterol, ischemic heart disease and diabetes.

Hypertension	68
High Cholesterol	60
Stroke	4
Ischemic Heart Disease	53
Depression	18
Chronic Kidney Disease	26
Asthma	7
Osteoporosis	9
Heart Failure	24
Chronic Obstructive Pulmonary Disease	9
Diabetes	28
Atrial Fibrillation	22
Dementia	6
Cancer	10

Education & Training

Dr. Karen P. Alexander, MD graduated from Duke University School of Medicine in 1992. She completed residency at Brigham and Women's Hospital. She is certified by the American Board of Internal Med, Cardiovascular Disease and has a state license in North Carolina.

Medical School: Duke University School of Medicine (1992)

Residency: Brigham and Women's Hospital (1995)

Board Certification: American Board of Internal Med, Cardiovascular Disease

Licensed In: North Carolina

Affiliations & Hospitals

Dr. Karen P. Alexander, MD is associated with these hospitals and organizations:

Duke Health

Insurance Information

Please note: Insurance information may change at any time, and the provider may accept your insurance plan even if it is not listed below. Please contact the provider's office to confirm that your insurance is accepted.

Dr. Karen P. Alexander, MD appears to accept the following insurance providers: MedCost, Aetna Traditional Choice, Aetna Medicare PPO, BlueCross BlueShield of North Carolina, CIGNA Open Access Plus, WellCare, Medicare Part B, AmeriHealth, Medicare Advantage, AARP, CIGNA Open Access, United Healthcare PPO, United Healthcare POS, United Healthcare HMO, Aetna, Aetna Workers' Compensation, TRICARE Prime, United Healthcare, Aetna Open Choice PPO, TRICARE Prime Remote, Medicare, Medicaid, Humana, Cigna, TRICARE, Harvard Pilgrim Health Care, Aetna Managed Choice POS, Gateway Health Alliance, Aetna HMO, Alliance Health (*Beginning January 2026), *Duke HomeCare and Hospice does not participate in the plan., Duke Employee Plans, Blue Options (123, PPO, HSA), *Duke HomeCare and Hospice and mental health providers do not participate with the plan., Aetna Quality Point of Service (QPOS), Aetna Choice POS, Aetna Choice POS II, Duke Advantage (*Beginning January 2026), Aetna Medicare Value Plan (HMO), Blue Advantage (*Available in select counties only), Duke Options (*Beginning January 2026), Duke Basic, Duke USA (*Beginning January 2026), Ambetter, Experience Health, Aetna Select HMO, Aetna PCP Coordinated POS Plan, Blue Select, Blue Medicare (HMO, PPO)*, Aetna Limited Benefit Insurance PPO, Vaya Health (*Beginning January 2026), Healthy Blue, Trillium (*Beginning January 2026), Aetna Health Network Only, Aetna Health Network Option, All Savers Fully Insured, Blue Value (*Duke Health Lake Norman and Kernodle Clinics only), First Medicare Direct, Carolina Complete Health, Healthgram, All Savers Alternate Funding, Aetna Medicare Assure Plan (HMO D-SNP), Aetna/CVS Health, Aetna Elect Choice HMO, Aetna Open Access Elect Choice, Partners (*Beginning January 2026), Aetna Voluntary Indemnity Group Plan, Duke Select, Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice, NC State Employees Health Plan, Ambetter of North Carolina and United Medical Resources (UMR).

Insurance Accepted by Provider includes:

According to our sources, Dr. Karen P. Alexander, MD accepts the following insurance providers:

MedCost

Aetna Traditional Choice

Aetna Medicare PPO

BlueCross BlueShield of North Carolina

CIGNA Open Access Plus

WellCare

Medicare Part B

AmeriHealth

Medicare Advantage

AARP

CIGNA Open Access

United Healthcare PPO

United Healthcare POS

United Healthcare HMO

Aetna

Aetna Workers' Compensation

TRICARE Prime

United Healthcare

Aetna Open Choice PPO

TRICARE Prime Remote

Medicare

Medicaid

Humana

Cigna

TRICARE

Harvard Pilgrim Health Care

Aetna Managed Choice POS

Gateway Health Alliance

Aetna HMO

Alliance Health (*Beginning January 2026)

*Duke HomeCare and Hospice does not participate in the plan.

Duke Employee Plans

Blue Options (123, PPO, HSA)

*Duke HomeCare and Hospice and mental health providers do not participate with the plan.

Aetna Quality Point of Service (QPOS)

Aetna Choice POS, Aetna Choice POS II

Duke Advantage (*Beginning January 2026)

Aetna Medicare Value Plan (HMO)

Blue Advantage (*Available in select counties only)

Duke Options (*Beginning January 2026)

Duke Basic

Duke USA (*Beginning January 2026)

Ambetter

Experience Health

Aetna Select HMO

Aetna PCP Coordinated POS Plan

Blue Select

Blue Medicare (HMO, PPO)*

Aetna Limited Benefit Insurance PPO

Vaya Health (*Beginning January 2026)

Healthy Blue

Trillium (*Beginning January 2026)

Aetna Health Network Only, Aetna Health Network Option

All Savers Fully Insured

Blue Value (*Duke Health Lake Norman and Kernodle Clinics only)

First Medicare Direct

Carolina Complete Health

Healthgram

All Savers Alternate Funding

Aetna Medicare Assure Plan (HMO D-SNP)

Aetna/CVS Health

Aetna Elect Choice HMO, Aetna Open Access Elect Choice

Partners (*Beginning January 2026)

Aetna Voluntary Indemnity Group Plan

Duke Select

Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice

NC State Employees Health Plan

Ambetter of North Carolina

United Medical Resources (UMR)

Ratings & Reviews

Dr. Karen P. Alexander, MD has an exceptional overall rating with an average of 4.89 out of 5 stars based on 436 ratings. We collect ratings and reviews of Dr. Karen P. Alexander, MD from all over the web to help you find the right in Durham, NC.

4.89

Overall Rating

(436 Ratings)

Leave a Review

Reviews Left On DocSpot

Overall Rating: 5.0 2017-01-31

I was referred to Dr. Alexander 6 years ago by my primary. She is a very caring person who makes the time with each patient to conclude issues responsibly.  She has an excellent named Jennifer who has been at Karen's side for some time providing seamless communication.

General Payments

These charts describe general payments received by Dr. Karen P. Alexander, MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Gilead Sciences Inc	$13,447 Ranexa $8,197	$5,250

**Types of Payments**
Honoraria	$12,750
Consulting Fee	$697

Research Payments

Dr. Karen P. Alexander, MD has received 38 research payments totaling $1,452,759.

Biography

Dr. Karen Alexander is a specialist in cardiology (heart disease). She works in Durham, NC and Morrisville, NC. Dr. Alexander has a 5.0 out of 5 star average patient rating. She usually honors Blue California, CIGNA Plans, and TRICARE, in addition to other insurance carriers. She studied medicine at Duke University School of Medicine. For her residency, Dr. Alexander trained at Brigham and Women's Hospital. She is affiliated with Duke Health. Dr. Alexander welcomes new patients at her office inMorrisville, NC as reported by Duke Health.