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Dr. Mary Ann Ann Knovich, MD, BS

(Dr. Mary Ann Knovich, MD)

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Specializes in: Medical Oncology and Adult Hematology

Penn State College of Medicine

Professional interests include: thrombophilia (clotting disorders), thrombosis (blood clots), bleeding, and more.

1021 Morehead Medical Drive Building 2 Suite 60201
Charlotte, NC 28204

(980) 442-4363

Dr. Mary Ann Ann Knovich, MD, BS is a medical oncologist in Charlotte, NC specializing in medical oncology and adult hematology. She graduated from Penn State College of Medicine. Dr. Mary Ann Ann Knovich, MD, BS is affiliated with Atrium Health and THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY.

Office Locations

Address:

1021 Morehead Medical Drive Building 2 Suite 60201
Charlotte, NC 28204

Some issues Dr. Mary Ann Ann Knovich, MD, BS can help you with:

Platelet Disorders

Platelet disorders are conditions caused by abnormally low or high levels of platelets in the blood, or by platelets that do not function correctly. Platelets are small blood cells that help stop bleeding by clumping together and forming blood clots, allowing the body to heal.

Thrombocytopenia is a disorder where people have too few platelets. With too few platelets in the bloodstream, the blood is unable to properly clot. People with thrombocytopenia may experience prolonged external and internal bleeding. Large purple bruises (ecchymoses) and small red skin spots (petechiae) in the skin and mouth are common in those with thrombocytopenia. Other symptoms of the disorder include bleeding gums, blood in bodily fluids, and fatigue. Thrombocytopenia most often arises from a different condition or treatment, such as alcoholism, autoimmune disease, cancer treatments, viruses (such as Hepatitis C and HIV), bone marrow diseases (such as leukemia and aplastic anemia), enlarged spleen, and exposure to toxic chemicals. In rare cases, thrombocytopenia is inherited.

Thrombocytosis is a disorder where people have too high of a concentration of platelets. Excess platelets can cause blood to clot in the veins. Blood clots in the veins are particularly dangerous, as they can obstruct blood flow and cause heart attacks and strokes. Thrombocytosis has two forms:

Thrombocythemia, also referred to as primary or essential thrombosis (ET), develops from irregular bone marrow cells that produce too many platelets. The cause of these bone marrow cells is unknown.
Reactive thrombosis (RT), also referred to as secondary thrombosis, arises from a different condition such as cancer, anemia, spleen removal, or infection. It is most common in older adults, but can occur in people of all ages. Symptoms of reactive thrombosis may gradually develop over time and typically include bruising, gum bleeding, and blood clotting.
Dysfunctional platelets are unable to perform the clotting function in the blood. People with dysfunctional platelets may have normal or low platelet counts. Causes of dysfunctional platelets include autoimmune disorders, hemolysis, infections, blood and bone marrow problems, and liver or kidney conditions.

If a doctor suspects a patient has a platelet disorder, a complete blood count (CBC) or platelet count test helps determine the concentration of platelets in a person's blood at a given time. Platelet disorders can be diagnosed by hematologists using advanced tests on platelet samples. Flow cytometry tests detect abnormalities by evaluating the characteristics of a platelet sample using targeted lasers and lights. Tests measuring prothrombin time (PT), or how long it takes for blood to clot, can also detect dysfunctional platelets. If platelets do not coagulate within a certain time frame, the patient most likely has dysfunctional platelets.

Treatments for low platelet counts include steroids like Prednisone, that can assist with platelet production. If a patient's low platelet count is caused by spleen problems, spleen removal (splenectomy) may be recommended. To treat the prolonged bleeding caused by thrombocytopenia, doctors frequently prescribe Dempressin, a hormone that promotes blood clotting. Antifibrinolytic medications such as tranexamic acid may also aid in the promotion of clotting and the prevention of bleeding. For patients with severe platelet disorders (either low platelet count and dysfunctional platelets), blood transfusions may be prescribed. Platelet blood transfusions deliver donated platelets to patients intravenously, replenishing the volume of functioning platelets.

Patients with high platelet counts are frequently prescribed a daily dose of over-the-counter medication aspirin. Platelet-lowering medications, such as hydroxyurea and Intron A, may reduce the likelihood of blood clot formation. Excess platelets may also be removed from the blood by a procedure called plateletpheresis or platelet reduction apheresis, where blood is drawn, circulated into a centrifuge that separates the blood components, and returned to the body with some platelets extracted. Plateletpheresis is a rare procedure reserved for patients who have severe clotting.

Patients can also modify their lifestyle to better manage their disorder and minimize complications. Patients with low blood counts should avoid blood-thinning medications, alcohol, and activities that could lead to injury. Patients with high blood count are advised to drink plenty of water, exercise regularly, and to avoid smoking. Many people with platelet disorders can live healthy and fulfilling lives with proper treatment and precautions.

Thrombocytopenia (Low Platelet Count)

If a doctor suspects a patient has a thrombocytopenia, a complete blood count (CBC) or platelet count test helps determine the concentration of platelets in a person's blood at a given time. Thrombocytopenia can be diagnosed by hematologists using advanced tests on platelet samples. Flow cytometry tests detect abnormalities by evaluating the characteristics of a platelet sample using targeted lasers and lights.

Patients can also modify their lifestyle to better manage their disorder and minimize complications. Patients with low blood counts should avoid blood-thinning medications, alcohol, and activities that could lead to injury. Many people with thrombocytopenia can live healthy and fulfilling lives with proper treatment and precautions.

doctor visit	184
hospital care	195
inpatient care	195

**Gender**
Male	116
Female	112

**Ethnicity**
Non-Hispanic White	154
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	61
From 75 to 84	39
85 and over	16
Less than 65	112

Hypertension	67
High Cholesterol	38
Stroke	12
Ischemic Heart Disease	35
Depression	31
Chronic Kidney Disease	49
Asthma	12
Osteoperosis	0
Atrial Fibrilation	17
Heart Failure	29
Chronic Obstructive Pulmonary Disease	20
Diabetes	36
Dementia	9
Cancer	11

doctor visit	41
hospital care	204
inpatient care	204
lab tests	19

**Gender**
Male	71
Female	92

**Ethnicity**
Non-Hispanic White	97
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	50
From 75 to 84	0
85 and over	0
Less than 65	73

Hypertension	75
High Cholesterol	49
Stroke	12
Ischemic Heart Disease	45
Depression	37
Chronic Kidney Disease	58
Asthma	13
Osteoperosis	8
Atrial Fibrilation	17
Heart Failure	39
Chronic Obstructive Pulmonary Disease	24
Diabetes	42
Dementia	13
Cancer	12

doctor visit	115
hospital care	230
inpatient care	230

**Gender**
Male	164
Female	158

**Ethnicity**
Non-Hispanic White	204
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	138
From 75 to 84	68
85 and over	22
Less than 65	94

Hypertension	74
High Cholesterol	55
Stroke	12
Ischemic Heart Disease	42
Depression	35
Chronic Kidney Disease	51
Asthma	14
Osteoperosis	9
Atrial Fibrilation	19
Heart Failure	34
Chronic Obstructive Pulmonary Disease	19
Diabetes	39
Dementia	11
Cancer	14

doctor visit	166
hospital care	168
inpatient care	168

**Gender**
Male	84
Female	81

**Ethnicity**
Non-Hispanic White	109
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	62
From 75 to 84	50
85 and over	0
Less than 65	0

Hypertension	70
High Cholesterol	48
Stroke	0
Ischemic Heart Disease	34
Depression	35
Chronic Kidney Disease	47
Asthma	23
Osteoperosis	10
Atrial Fibrilation	16
Heart Failure	23
Chronic Obstructive Pulmonary Disease	21
Diabetes	32
Dementia	12
Cancer	8

doctor visit	180
hospital care	97
inpatient care	97

**Gender**
Male	76
Female	91

**Ethnicity**
Non-Hispanic White	125
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	76
From 75 to 84	42
85 and over	11
Less than 65	38

Hypertension	70
High Cholesterol	47
Stroke	0
Ischemic Heart Disease	33
Depression	32
Chronic Kidney Disease	50
Asthma	10
Osteoperosis	16
Atrial Fibrilation	17
Heart Failure	26
Chronic Obstructive Pulmonary Disease	18
Diabetes	30
Dementia	11
Cancer	10

doctor visit	202
hospital care	119
inpatient care	119

**Gender**
Male	68
Female	107

**Ethnicity**
Non-Hispanic White	127
Black	36
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	78
From 75 to 84	47
85 and over	13
Less than 65	37

Hypertension	73
High Cholesterol	54
Stroke	9
Ischemic Heart Disease	39
Depression	33
Chronic Kidney Disease	47
Asthma	7
Osteoperosis	12
Atrial Fibrilation	17
Heart Failure	33
Chronic Obstructive Pulmonary Disease	14
Diabetes	31
Dementia	12
Cancer	17

doctor visit	180
hospital care	93
inpatient care	93

**Gender**
Male	79
Female	97

**Ethnicity**
Non-Hispanic White	130
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	87
From 75 to 84	34
85 and over	19
Less than 65	36

Hypertension	74
High Cholesterol	52
Stroke	7
Ischemic Heart Disease	36
Depression	34
Chronic Kidney Disease	48
Asthma	7
Osteoperosis	12
Atrial Fibrilation	15
Heart Failure	25
Chronic Obstructive Pulmonary Disease	13
Diabetes	31
Dementia	9
Cancer	13

doctor visit	163
hospital care	17
inpatient care	17

**Gender**
Male	63
Female	74

**Ethnicity**
Non-Hispanic White	99
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	61
From 75 to 84	37
85 and over	12
Less than 65	27

Hypertension	66
High Cholesterol	47
Stroke	8
Ischemic Heart Disease	35
Depression	30
Chronic Kidney Disease	45
Asthma	0
Osteoperosis	0
Atrial Fibrilation	18
Heart Failure	23
Chronic Obstructive Pulmonary Disease	12
Diabetes	29
Dementia	11
Cancer	11

doctor visit	296
hospital care	83
inpatient care	83

Average Medicare Procedure Volume From 2013 - 2021

Volume of procedures performed by Dr. Mary Ann Ann Knovich, MD, BS for Medicare patients.

The highest averages for the top procedures that Dr. Mary Ann Ann Knovich, MD, BS treated as a medical oncologist in Charlotte, NC were hospital care, inpatient care and lab tests.

doctor visit	169
hospital care	134
inpatient care	134
lab tests	19

Average Medicare Patient Data From 2013 - 2021

Information about Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS.

**Gender**
Male	72
Female	81

**Ethnicity**
Black / African American	3
Asian / Pacific Islander	0
Non-Hispanic White	104
Native American / Alaskan Native	0
Hispanic	0
Other	0

**Age**
75 to 84	31
85 and over	9
Less than 65	41
65 to 74	61

Average of Total of Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS From 2013 - 2021

The highest averages of the most common conditions of Medicare patients that Dr. Mary Ann Ann Knovich, MD, BS treated were hypertension, chronic kidney disease, high cholesterol and ischemic heart disease.

Hypertension	56
High Cholesterol	39
Stroke	6
Ischemic Heart Disease	29
Depression	26
Chronic Kidney Disease	39
Asthma	8
Osteoporosis	6
Heart Failure	23
Chronic Obstructive Pulmonary Disease	14
Diabetes	27
Atrial Fibrillation	13
Cancer	9
Dementia	8

Education & Training

Dr. Mary Ann Ann Knovich, MD, BS graduated from Penn State College of Medicine. She completed residency at Wake Forest University Baptist Medical Center. She is certified by the American Board of Internal Medicine, Hematology and has a state license in North Carolina.

Medical School: Penn State College of Medicine

Residency: Wake Forest University Baptist Medical Center

Board Certification: American Board of Internal Medicine, Hematology

Licensed In: North Carolina

Affiliations & Hospitals

Dr. Mary Ann Ann Knovich, MD, BS is associated with these hospitals and organizations:

Atrium Health

THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY

Ratings & Reviews

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General Payments

These charts describe general payments received by Dr. Mary Ann Ann Knovich, MD, BS. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Alexion Pharmaceuticals, Inc.	$319 SOLIRIS $319
Novo Nordisk Inc	$119 NovoSeven RT $18	Novoeight $13	$88
Grifols USA, LLC	$51 Alphanate $51
Bioverativ Therapeutics Inc.	$46 $46
GENZYME CORPORATION	$45 NO PRODUCT DISCUSSED $45
Other	$53 BENEFIX $23	JADENU $16	ELIQUIS $15

**Types of Payments**
Food and Beverage	$519
Education	$113

Biography

Dr. Mary Knovich specializes in oncology (cancer care) and adult hematology and practices in Charlotte, NC. She is professionally affiliated with Atrium Health. She is a graduate of Penn State College of Medicine.

Select Year:

Dr. Mary Ann Ann Knovich, MD, BS

Office Locations

Some issues Dr. Mary Ann Ann Knovich, MD, BS can help you with:

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

2013 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2013

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

2014 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2014

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

2015 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2015

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

2016 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2016

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

2017 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2017

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

2018 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2018

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

2019 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2019

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

2020 Medicare Patient Data

Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS in 2020

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

Average Medicare Procedure Volume From 2013 - 2021

Average Medicare Patient Data From 2013 - 2021

Average of Total of Conditions of Medicare patients treated by Dr. Mary Ann Ann Knovich, MD, BS From 2013 - 2021

Education & Training

Affiliations & Hospitals

Ratings & Reviews

General Payments

Biography

Other Providers in Charlotte, NC